N-(5-Isobutyl-1,3,4-thiadiazol-2-yl)-p-toluenesulfonamide
Names
[ CAS No. ]:
3572-41-6
[ Name ]:
N-(5-Isobutyl-1,3,4-thiadiazol-2-yl)-p-toluenesulfonamide
[Synonym ]:
5-p-Tolylsulfonylamino-2-isobutyl-1,3,4-thiadiazol
2-p-Methylbenzenesulfonamido-5-isobutyl-1,3,4-thiadiazole
5-p-Toluolsulfonylamino-2-isobutyl-1,3,4-thiadiazol
FWH 106
Chemical & Physical Properties
[ Density]:
1.314g/cm3
[ Boiling Point ]:
464.7ºC at 760 mmHg
[ Molecular Formula ]:
C13H17N3O2S2
[ Molecular Weight ]:
311.42300
[ Flash Point ]:
234.8ºC
[ Exact Mass ]:
311.07600
[ PSA ]:
108.57000
[ LogP ]:
3.99960
[ Index of Refraction ]:
1.597
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- XT5830000
- CHEMICAL NAME :
- p-Toluenesulfonamide, N-(5-isobutyl-1,3,4-thiadiazol-2-yl)-
- CAS REGISTRY NUMBER :
- 3572-41-6
- BEILSTEIN REFERENCE NO. :
- 0271816
- LAST UPDATED :
- 199707
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C13-H17-N3-O2-S2
- MOLECULAR WEIGHT :
- 311.45
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2400 mg/kg
- TOXIC EFFECTS :
- Behavioral - ataxia Endocrine - hypoglycemia Nutritional and Gross Metabolic - body temperature decrease
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 4,631,1962
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1650 mg/kg
- TOXIC EFFECTS :
- Behavioral - ataxia Endocrine - hypoglycemia Nutritional and Gross Metabolic - body temperature decrease
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 4,631,1962
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 270 mg/kg
- TOXIC EFFECTS :
- Behavioral - ataxia Endocrine - hypoglycemia Nutritional and Gross Metabolic - body temperature decrease
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 4,631,1962
Safety Information
[ HS Code ]:
2935009090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2935009090
[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%