(S)-2,3-Dihydro-6-(2-hydroxyethyl)-2-(hydroxymethyl)-2,5,7-trimethyl-1H-inden-1-one

Names

[ Name ]:
(S)-2,3-Dihydro-6-(2-hydroxyethyl)-2-(hydroxymethyl)-2,5,7-trimethyl-1H-inden-1-one

[Synonym ]:
(S)-6-(2-Hydroxy-ethyl)-2-hydroxymethyl-2,5,7-trimethyl-indan-1-one
(2S)-Pterosin-A
(2S)-Pterosin A
Pterosin A
pterosin A

Biological Activity

[Description]:

Pterosin A is an orally active anti-diabetic agent. Pterosin A promotes glucose uptake, increases serum insulin, and improves hyperglycemia and glucose intolerance in diabetic mice. Pterosin A can be isolated from Pteridium aquilinum[1][2].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[References]

[1]. Hsu FL, et al. Antidiabetic effects of pterosin A, a small-molecular-weight natural product, on diabetic mouse models. Diabetes. 2013 Feb;62(2):628-38.

[2]. Chen CY, et al. Chemical constituents analysis and antidiabetic activity validation of four fern species from Taiwan. Int J Mol Sci. 2015 Jan 22;16(2):2497-516.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₅H₂₀O₃

[ Molecular Weight ]:
248.32

[ Exact Mass ]:
248.14100

[ PSA ]:
57.53000

[ LogP ]:
1.57560