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(2H7)-1-Naphthyl methylcarbamate

Names

[ CAS No. ]:
362049-56-7

[ Name ]:
(2H7)-1-Naphthyl methylcarbamate

[Synonym ]:
1-Naphthalen-d-ol, methylcarbamate
OMS-29-d7
1-Naphthyl-d7 N-Methylcarbamate
1-Naphtyl N-Methylcarbamate-d7
Carbaryl-d7
Derbac-d7
(H)-1-Naphthyl methylcarbamate
Ravyon-d7
Sevin-d7
Carylderm-d7

Biological Activity

[Description]:

Carbaryl-d7 is the deuterium labeled Carbaryl[1]. Carbaryl is used chiefly as an insecticide[2].

[Related Catalog]:

Research Areas >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Nancy E Todd, et al. Effects of Sevin (Carbaryl Insecticide) on Early Life Stages of Zebrafish (Danio Rerio). Ecotoxicol Environ Saf. 2002 Oct;53(2):267-72.  

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
329.3±15.0 °C at 760 mmHg

[ Melting Point ]:
142ºC

[ Molecular Formula ]:
C12H4D7NO2

[ Molecular Weight ]:
208.264

[ Flash Point ]:
153.0±20.4 °C

[ Exact Mass ]:
208.122910

[ PSA ]:
38.33000

[ LogP ]:
2.40

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.611

Related Compounds