4-(chloromethyl)-2-methyl-2-pentyl-1,3-dioxolane
Names
[ CAS No. ]:
36236-73-4
[ Name ]:
4-(chloromethyl)-2-methyl-2-pentyl-1,3-dioxolane
[Synonym ]:
AY-22,352
4-Chloromethyl-2-methyl-2-pentyl-1,3-dioxolane
1,3-DIOXALANE,4-CHLOROMETHYL-2-METHYL-2-PENTYL
Chemical & Physical Properties
[ Density]:
0.99g/cm3
[ Boiling Point ]:
253.6ºC at 760 mmHg
[ Molecular Formula ]:
C10H19ClO2
[ Molecular Weight ]:
206.71000
[ Flash Point ]:
71.6ºC
[ Exact Mass ]:
206.10700
[ PSA ]:
18.46000
[ LogP ]:
2.93710
[ Index of Refraction ]:
1.434
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- JH6960000
- CHEMICAL NAME :
- 1,3-Dioxalane, 4-chloromethyl-2-methyl-2-pentyl-
- CAS REGISTRY NUMBER :
- 36236-73-4
- LAST UPDATED :
- 198910
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C10-H19-Cl-O2
- MOLECULAR WEIGHT :
- 206.74
- WISWESSER LINE NOTATION :
- T5O COTJ B5 B1 D1G
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 50 mg/kg
- SEX/DURATION :
- male 20 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count) Reproductive - Fertility - male fertility index (e.g. # males impregnating females per # males exposed to fertile nonpregnant females)
- REFERENCE :
- JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960- Volume(issue)/page/year: 30,117,1972
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 25200 ug/kg
- SEX/DURATION :
- male 3 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Fertility - male fertility index (e.g. # males impregnating females per # males exposed to fertile nonpregnant females)
- REFERENCE :
- BIREBV Biology of Reproduction. (Soc. for the Study of Reproduction, 309 W. Clark St., Champaign, IL 61820) V.1- 1969- Volume(issue)/page/year: 14,202,1976
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 30300 ug/kg
- SEX/DURATION :
- male 3 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Fertility - male fertility index (e.g. # males impregnating females per # males exposed to fertile nonpregnant females)
- REFERENCE :
- BIREBV Biology of Reproduction. (Soc. for the Study of Reproduction, 309 W. Clark St., Champaign, IL 61820) V.1- 1969- Volume(issue)/page/year: 14,202,1976
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 111 mg/kg
- SEX/DURATION :
- male 3 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Fertility - male fertility index (e.g. # males impregnating females per # males exposed to fertile nonpregnant females)
- REFERENCE :
- JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960- Volume(issue)/page/year: 43,281,1975