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Guaiacin

Names

[ CAS No. ]:
36531-08-5

[ Name ]:
Guaiacin

[Synonym ]:
2-Naphthalenol, 5,6,7,8-tetrahydro-8-(4-hydroxy-3-methoxyphenyl)-3-methoxy-6,7-dimethyl-, (6R,7S,8S)-
(+)-guaiacin
Guaiacin
(6R,7S,8S)-8-(4-Hydroxy-3-methoxyphenyl)-3-methoxy-6,7-dimethyl-5,6,7,8-tetrahydro-2-naphthalenol

Biological Activity

[Description]:

Guaiacin is a arylnaphthalene type lignin isolated from the barks of Machilus thunbergii SIEB. et ZUCC (Lauraceae). Guaiacin significantly increases alkaline phosphatase activity and osteoblast differentiation[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Metabolic Disease

[References]

[1]. Lee MK, et al. Stimulatory activity of lignans from Machilus thunbergii on osteoblast differentiation. Biol Pharm Bull. 2007 Apr;30(4):814-7.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
484.5±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C20H24O4

[ Molecular Weight ]:
328.402

[ Flash Point ]:
246.8±28.7 °C

[ Exact Mass ]:
328.167450

[ PSA ]:
58.92000

[ LogP ]:
4.06

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.573

Related Compounds