<Suppliers Price>

Galanin (2-11) amide trifluoroacetate salt

Names

[ CAS No. ]:
367518-31-8

[ Name ]:
Galanin (2-11) amide trifluoroacetate salt

[Synonym ]:
Dynole 34-2
Galanin (2-11)

Biological Activity

[Description]:

AR-M1896 is a GalR2 selective agonist with a binding IC50 of 1.76 nM for rat GalR2. AR-M1896 can be used for the research of acute myocardial infarction and neuropathic pain[1][2].

[Related Catalog]:

Research Areas >> Neurological Disease
Signaling Pathways >> GPCR/G Protein >> Neuropeptide Y Receptor

[Target]

IC50: 1.76 nM (rat GalR2), 879 nM (hGalR1)[1]


[References]

[1]. Liu HX, et al. Receptor subtype-specific pronociceptive and analgesic actions of galanin in the spinal cord: selective actions via GalR1 and GalR2 receptors. Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9960-4.  

[2]. Serebryakova L, et al. Galanin and its N-terminal fragments reduce acute myocardial infarction in rats. Peptides. 2019 Jan;111:127-131.  

Chemical & Physical Properties

[ Molecular Formula ]:
C54H81N13O14

[ Molecular Weight ]:
1136.30

[ Exact Mass ]:
1135.60000

[ PSA ]:
450.58000

[ LogP ]:
2.49160

Related Compounds