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10-Shogaol

Names

[ CAS No. ]:
36752-54-2

[ Name ]:
10-Shogaol

[Synonym ]:
10-Shogaol

Biological Activity

[Description]:

[10]-Shogaol is an antioxidant from Zingiber officinale for human skin cell growth and a migration enhancer. [10]-Shogaol inhibits COX-2 with an IC50 of 7.5 μM and has antiproliferation activity[1][2][3].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Immunology/Inflammation >> COX

[Target]

COX-2:7.5 μM (IC50)


[References]

[1]. Chen CY, et al. 10-Shogaol, an antioxidant from Zingiber officinale for skin cell proliferation and migration enhancer. Int J Mol Sci. 2012;13(2):1762-77.

[2]. van Breemen RB, et al. Cyclooxygenase-2 inhibitors in ginger (Zingiber officinale). Fitoterapia. 2011 Jan;82(1):38-43.

[3]. Liu CM, et al. Ginger Phytochemicals Inhibit Cell Growth and Modulate Drug Resistance Factors in Docetaxel Resistant Prostate Cancer Cell. Molecules. 2017 Sep 5;22(9). pii: E1477.

Chemical & Physical Properties

[ Molecular Formula ]:
C21H32O3

[ Molecular Weight ]:
332.47700

[ Exact Mass ]:
332.23500

[ PSA ]:
46.53000

[ LogP ]:
5.59940

[ Storage condition ]:
2-8℃

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Related Compounds