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Tempone-d16

Names

[ CAS No. ]:
36763-53-8

[ Name ]:
Tempone-d16

[Synonym ]:
4-Oxo-2,2,6,6-tetramethylpiperidine-d16,1-15N-1-oxyl
2,2,6,6-tetramethyl-4-piperidone-N-oxyl-d16
Perdeutero-2,2,6,6-tetramethyl-4-piperidon-N-oxid
4-Oxo-TEMPO-d16,1-15N,free radical
4-Oxo-TEMPO-d16,free radical
Perdeutero-1-oxyl-2,2,6,6-tetramethyl-4-piperidone
TEMPONE-d16,1-15N
4-oxo-2,2,6,6-tetramethylpiperidine-d16-1-oxyl
TEMPONE-d16
4-Oxo-,2,2,6,6-tetramethylpiperidine-d16-1-oxyl,TEMPONE-d16
MFCD01075420

Biological Activity

[Description]:

Tempone-d16 is the deuterium labeled Tempone[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

Chemical & Physical Properties

[ Melting Point ]:
35ºC(lit.)

[ Molecular Formula ]:
C9D16NO2

[ Molecular Weight ]:
186.32700

[ Exact Mass ]:
186.21900

[ PSA ]:
20.31000

[ LogP ]:
1.49190

MSDS

Safety Information

[ Symbol ]:

GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H400

[ Precautionary Statements ]:
P273

[ RIDADR ]:
UN 3077 9 / PGIII

[ WGK Germany ]:
3

Synthetic Route

Precursor & DownStream


Related Compounds