silybin (mixture of silybin a and silybin b)

Names

[ Name ]:
silybin (mixture of silybin a and silybin b)

[Synonym ]:
Silybin
S0508

Biological Activity

[Description]:

(±)-Silybin is the racemate of Silybin (HY-N0779A). Silybin induces apoptosis and exhibits hepatoprotective, antioxidant, anti-inflammatory, anti-cancer activity[1][2].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Silvia Zappavigna, et al. Silybin-Induced Apoptosis Occurs in Parallel to the Increase of Ceramides Synthesis and miRNAs Secretion in Human Hepatocarcinoma Cells. Int J Mol Sci. 2019 May 3;20(9):2190.

[2]. Runbin Sun, et al. Silybin ameliorates hepatic lipid accumulation and modulates global metabolism in an NAFLD mouse model. Biomed Pharmacother. 2020 Mar;123:109721.

Chemical & Physical Properties

[ Density]:
1.527g/cm3

[ Boiling Point ]:
793ºC at 760 mmHg

[ Melting Point ]:
160ºC

[ Molecular Formula ]:
C₂₅H₂₂O₁₀

[ Molecular Weight ]:
482.44

[ Flash Point ]:
274.4ºC

[ Exact Mass ]:
481.11300

[ PSA ]:
159.05000

[ LogP ]:
3.38430

[ Index of Refraction ]:
1.684

[ Storage condition ]:
Freezer

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xi

[ RTECS ]:
DJ2981770