ethyl 4-phenyl-1-(2-phenylmethoxyethyl)piperidine-4-carboxylate

Controlled Substances

Psychoactive Drugs/Narcotic Drugs/Hypertoxic Chemicals/Non-Medical Use of Narcotic Drugs and Psychotropic Substances

Names

[ Name ]:
ethyl 4-phenyl-1-(2-phenylmethoxyethyl)piperidine-4-carboxylate

[Synonym ]:
1-(2-benzyloxy-ethyl)-4-phenyl-piperidine-4-carboxylic acid ethyl ester
Benzetidina [INN-Spanish]
Ethyl 1-(2-benzyloxyethyl)-4-phenylpiperidine-4-carboxylate
NIH 7574
DEA No. 9606
Benzethidin
1-(2-Benzyloxy-ethyl)-4-phenyl-4-ethoxycarbonyl-piperidin
1-(2-Benzyloxy-aethyl)-4-phenyl-piperidin-4-carbonsaeure-aethylester
BENZETHIDINE
Benzethidinum [INN-Latin]
Benzethidine [INN:BAN:DCF]

Chemical & Physical Properties

[ Density]:
1.095 g/cm3

[ Boiling Point ]:
467.8ºC at 760mmHg

[ Molecular Formula ]:
C₂₃H₂₉NO₃

[ Molecular Weight ]:
367.48100

[ Flash Point ]:
236.7ºC

[ Exact Mass ]:
367.21500

[ PSA ]:
38.77000

[ LogP ]:
3.73800

[ Index of Refraction ]:
1.549

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NS5265500

CHEMICAL NAME :: Isonipecotic acid, 1-(2-(benzyloxy)ethyl)-4-phenyl-, ethyl ester

CAS REGISTRY NUMBER :: 3691-78-9

BEILSTEIN REFERENCE NO. :: 0334584

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C23-H29-N-O3

MOLECULAR WEIGHT :: 367.53

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 284 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 15,254,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 600 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 15,254,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 10900 ug/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 15,254,1960