ROS kinases-IN-1
Names
[ CAS No. ]:
370096-57-4
[ Name ]:
ROS kinases-IN-1
Biological Activity
[Description]:
ROS kinases-IN-1 (pag 98) is a ROS tyrosine kinase inhibitor with IC50 value of 1.22 μM. ROS kinases-IN-1 shows anti-tumor activity[1].
[Related Catalog]:
[Target]
IC50: 1.22 μM (ROS kinase)[1]
[In Vitro]
ROS kinases-IN-1 (1-100 μM; 1 d) inhibits the growth of cervical cancer cell and glioblastoma cells[1]. Cell Viability Assay[1] Cell Line: HeLa, U138, U87, LN18, and U118 cells Concentration: 1, 10, and 100 μM Incubation Time: one day Result: Showed EC50s for HeLa, U138, U87, LN18, and U118 cells of 20, 8, 8, 12, and 7 μM, respectively.
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C20H16N4O
[ Molecular Weight ]:
328.373