Endo-β-N-acetylglucosaminidase (Endo A)

Names

[ Name ]:
Endo-β-N-acetylglucosaminidase (Endo A)

[Synonym ]:
MFCD00151069

Biological Activity

[Description]:

Endo-β-N-acetylglucosaminidase (Endo A) is an Endo-β-N-acetylglucosaminidases (ENGases) from Arthrobacter protophormiae. Endo-A can transfer a high-mannose type oligosaccharide to monosaccharides such as N-acetylglucosamine (GlcNAc) and glucose to form a new oligosaccharide. Endo-A catalyzes glycopeptide synthesis by using Man3GlcNAc-oxazoline[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Yin J, et al. Structural basis and catalytic mechanism for the dual functional endo-beta-N-acetylglucosaminidase A. PLoS One. 2009;4(3):e4658.

Chemical & Physical Properties

[ Boiling Point ]:
100.0 °C

[ Storage condition ]:
2-8°C

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)

[ RIDADR ]:
NONH for all modes of transport

Articles

Improved plasma membrane expression of the trafficking defective P344R mutant of muscle, skeletal, receptor tyrosine kinase (MuSK) causing congenital myasthenic syndrome.

Int. J. Biochem. Cell Biol. 60 , 119-29, (2015)

Muscle, skeletal, receptor tyrosine kinase (MuSK) is a key organizer at the postsynaptic membrane and critical for proper development and maintenance of the neuromuscular junction. Mutations in MUSK r...

A cholesterol consensus motif is required for efficient intracellular transport and raft association of a group 2 HA from influenza virus.

Biochem. J. 465(2) , 305-14, (2015)

The HA (haemagglutinin) of influenza viruses must be recruited to membrane rafts to perform its function in membrane fusion and virus budding. We previously showed using FRET that deletion of the two ...

Proteome analysis of the farnesol-induced stress response in Aspergillus nidulans--The role of a putative dehydrin.

J. Proteomics 75(13) , 4038-49, (2012)

The isoprenoid alcohol farnesol represents a quorum-sensing molecule in pathogenic yeasts, but was also shown to inhibit the growth of many filamentous fungi. In order to gain a deeper insight into th...