Kisspeptin-13 (human) trifluoroacetate salt

Kisspeptin 13 is a GPR54 and GnRH receptor activator, an endogenous active isoform. Kisspeptin 13 enhances memory and can be used in Alzheimer's disease research[1].

Signaling Pathways >> GPCR/G Protein >> GNRH Receptor

Research Areas >> Neurological Disease

Kisspeptin 13 (intracerebroventricular administration; 2 μg/side; once) treatment improves object recognition memory impairment induced by Aβ through activation of GPR54 and GnRH receptor[1]. Animal Model: Male Swiss mice with memory impairment induced by A-beta[1] Dosage: 2 μg/side Administration: Intracerebroventricular administration; 2 μg/side; once Result: Facilitated memory formation and prolonged memory retention through activation of the GPR54 and GnRH receptors, and suppressed memory-impairing effect of Aβ through activation of the GPR54.