ALLO-1

Names

[ Name ]:
ALLO-1

[Synonym ]:
1-Benzyl-3-(4-carbamoylphenoxy)-pyrrolidin
1-benzyl-3-(4-chloro-phenyl)-5-methyl-imidazolidine-2,4-dione
Benzamide,p-[(1-benzyl-3-pyrrolidinyl)oxy]-(8CI)
3-(4-Chlorophenyl)-5-methyl-1-(phenylmethyl)-2,4-Imidazolidinedione
Benzamide,4-[[1-(phenylmethyl)-3-pyrrolidinyl]oxy]
4-(1-BENZYLPYRROLIDIN-3-YLOXY)BENZAMIDE

Biological Activity

[Description]:

ALLO-1, an autophagy receptor, is essential for autophagosome formation around paternal organelles and directly binds to the worm LC3 homologue LGG-1 through its LC3-interacting region (LIR) motif[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Autophagy >> Autophagy

[Target]

Autophagy[1]

[References]

[1]. Sato M, et al. The autophagy receptor ALLO-1 and the IKKE-1 kinase control clearance of paternal mitochondria in Caenorhabditis elegans. Nat Cell Biol. 2018 Jan;20(1):81-91.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₇H₁₅ClN₂O₂

[ Molecular Weight ]:
314.77

[ Exact Mass ]:
314.08200

[ PSA ]:
40.62000

[ LogP ]:
3.70020

[ Storage condition ]:
2-8℃

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H317-H319-H400

[ Precautionary Statements ]:
P273-P280-P305 + P351 + P338

[ RIDADR ]:
UN 3077 9 / PGIII

[ HS Code ]:
2933990090

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%