Ponceau 2R
Names
[ CAS No. ]:
3761-53-3
[ Name ]:
Ponceau 2R
[Synonym ]:
red101
1695red
aizen ponceau rh
Acid Red 26
xylidine red
ponceauj
ponceaug
java ponceau 2R
acid ponceau r
calcocid scarlet 2R
c.i.79
acetacid red j
scarlet 2R
MFCD00003897
pigment ponceau r
new ponceau 4R
ahcocid fast scarlet r
acilan ponceau rrl
Xylidine ponceau 2R
hexacol ponceau 2R
Ponceau MX
amacid scarlet 2R
EINECS 223-178-3
naphthazine scarlet 2R
Disodium 4-[(E)-(2,4-dimethylphenyl)diazenyl]-3-hydroxy-2,6-naphthalenedisulfonate
redr
Ponceau Red R
certicol ponceau mxs
Disodium 4-[(E)-(2,4-dimethylphenyl)diazenyl]-3-hydroxynaphthalene-2,6-disulfonate
neklacid red rr
ponceaugr
edicol ponceau rs
acid scarlet
paper red hrr
comacid scarlet 2R
BRILLIANT PONCEAU G
2,6-naphthalenedisulfonic acid, 4-[(E)-(2,4-dimethylphenyl)azo]-3-hydroxy-, disodium salt
hispacid ponceau r
2,6-Naphthalenedisulfonic acid, 4-[(E)-2-(2,4-dimethylphenyl)diazenyl]-3-hydroxy-, sodium salt (1:2)
naphthalene scarlet r
Acid Red 26,Ponceau 2 R,Xylidine ponceau 2R
Ponceau de Xylidine
Ponceau 2R
Dinatrium-4-[(E)-(2,4-dimethylphenyl)diazenyl]-3-hydroxy-2,6-naphthalendisulfonat
ponceaufr
Ponceau Xylidine
4-[(E)-(2,4-Diméthylphényl)diazènyl]-3-hydroxy-2,6-naphtalènedisulfonate de disodium
kiton ponceau 2R
AKA503
lake scarlet r
D & C red no. 5
Xylidine ponceau
acid scarlet 2R
calcolake scarlet 2R
Biological Activity
[Description]:
[Related Catalog]:
Chemical & Physical Properties
[ Molecular Formula ]:
C18H14N2Na2O7S2
[ Molecular Weight ]:
480.422
[ Exact Mass ]:
480.003784
[ PSA ]:
176.11000
[ LogP ]:
5.54740
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QJ6825000
- CHEMICAL NAME :
- 2,7-Naphthalenedisulfonic acid, 3-hydroxy-4-(2,4-xylylazo)-, disodium salt
- CAS REGISTRY NUMBER :
- 3761-53-3
- LAST UPDATED :
- 199707
- DATA ITEMS CITED :
- 20
- MOLECULAR FORMULA :
- C18-H14-N2-O7-S2.2Na
- MOLECULAR WEIGHT :
- 480.44
- WISWESSER LINE NOTATION :
- L66J BNUNR B1 D1& CQ DSWQ HSWQ &-NA- 2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 23160 mg/kg
- TOXIC EFFECTS :
- Behavioral - muscle weakness Behavioral - ataxia
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >6600 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2 gm/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - antipsychotic
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1530 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 45 gm/kg/90D-C
- TOXIC EFFECTS :
- Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight Endocrine - changes in spleen weight
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 136 gm/kg/81W-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 35 gm/kg/52W
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors
MUTATION DATA
- TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 63 mg/kg
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 108,225,1983 *** REVIEWS *** IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 8,189,1975 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 8,189,1975 IARC Cancer REIEW:Group 2B IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M3143 No. of Facilities: 212 (estimated) No. of Industries: 4 No. of Occupations: 6 No. of Employees: 2142 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M3143 No. of Facilities: 131 (estimated) No. of Industries: 3 No. of Occupations: 4 No. of Employees: 1200 (estimated) No. of Female Employees: 874 (estimated)
Safety Information
[ Symbol ]:
GHS08
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H351
[ Precautionary Statements ]:
P281
[ Personal Protective Equipment ]:
Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
[ Hazard Codes ]:
Xn:Harmful;
[ Risk Phrases ]:
R20/21;R33
[ Safety Phrases ]:
36-53-45
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
QJ6825000
Articles
J. Pharmacol. Exp. Ther. 350(1) , 79-88, (2014)
Idiopathic pulmonary fibrosis is thought to involve lung injury caused by reactive oxygen species (ROS), which in turn is followed by abnormal fibrosis. A transforming growth factor (TGF)-β1-induced i...
Development of a simple procedure for the treatment of femoral head osteonecrosis with intra-osseous injection of bone marrow mesenchymal stromal cells: study of their biodistribution in the early time points after injection.Stem Cell Res. Ther. 6 , 68, (2015)
Osteonecrosis of the femoral head (ONFH) is a degenerative disease progressing to a femoral head (FH) collapse. Injection of osteoprogenitor cells like bone marrow mesenchymal stromal cells (BMSCs) in...
Comparative Labeling of Equine and Ovine Multipotent Stromal Cells With Superparamagnetic Iron Oxide Particles for Magnetic Resonance Imaging In Vitro.Cell. Transplant. 24 , 1111-25, (2015)
The purpose of this study was to evaluate the use of three different superparamagnetic iron oxide (SPIO) particles for labeling of ovine and equine bone marrow (BM)-derived multipotent stromal cells (...