2',3',5'-Tri-O-benzoyl-5-Methoxyuridine

Names

[ Name ]:
2',3',5'-Tri-O-benzoyl-5-Methoxyuridine

[Synonym ]:
O2',O3',O5'-tribenzoyl-5-methoxy-uridine

Biological Activity

[Description]:

2’,3’,5’-Tri-O-benzoyl-5-methoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₁H₂₆N₂O₁₀

[ Molecular Weight ]:
586.55

[ Exact Mass ]:
586.15900

[ PSA ]:
152.22000

[ LogP ]:
2.75080

2',3',5'-Tri-O-benzoyl-5-Methoxyuridine

Names

Biological Activity

Chemical & Physical Properties

Related Compounds