Cimifugin

Names

[ Name ]:
Cimifugin

[Synonym ]:
(2R)-7-(Hydroxymethyl)-2-(2-hydroxy-2-propanyl)-4-methoxy-2,3-dihydro-5H-furo[3,2-g]chromen-5-one
5H-Furo[3,2-g][1]benzopyran-5-one, 2,3-dihydro-7-(hydroxymethyl)-2-(1-hydroxy-1-methylethyl)-4-methoxy-, (2R)-
(2S)-7-(Hydroxymethyl)-2-(2-hydroxypropan-2-yl)-4-methoxy-2,3-dihydro-5H-furo[3,2-g]chromen-5-one
5H-Furo[3,2-g][1]benzopyran-5-one, 2,3-dihydro-7-(hydroxymethyl)-2-(1-hydroxy-1-methylethyl)-4-methoxy-, (2S)-
Cimifugin
I07-0216
(2S)-7-(Hydroxymethyl)-2-(2-hydroxy-2-propanyl)-4-methoxy-2,3-dihydro-5H-furo[3,2-g]chromen-5-one
N1342

Biological Activity

[Description]:

Cimifugin is a major components of Yu-ping-feng-san, a Chinese medical formula that is used clinically for allergic diseases and characterized by reducing allergy relapse.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Natural Products >> Others

Research Areas >> Inflammation/Immunology

[References]

[1]. Shen D, et al. Screening active components from Yu-ping-feng-san for regulating initiative key factors in allergic sensitization. PLoS One. 2014 Sep 8;9(9):e107279.

[2]. Wang X, et al. Pharmacokinetics of cimifugin in rat plasma after oral administration of the extract of Saposhnikovia divaricatae root. Determination of cimifugin by high performance liquid chromatography coupled with solid phase extraction. Arzneimittelfo

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
546.4±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₆H₁₈O₆

[ Molecular Weight ]:
306.310

[ Flash Point ]:
204.9±23.6 °C

[ Exact Mass ]:
306.110352

[ PSA ]:
89.13000

[ LogP ]:
1.21

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.599

[ Storage condition ]:
-20°C

Cimifugin

Names

Biological Activity

Chemical & Physical Properties

Precursor & DownStream

Precursor

DownStream

Related Compounds