CB-6673567

Names

[ Name ]:
CB-6673567

Biological Activity

[Description]:

CB-6673567 is a potent, selective Adenylyl Cyclase 1 (AC1) inhibitor with IC50 of 77 uM, displays a 2- to 4-fold isoform selectivity over AC6; blocks the choline-induced cAMP increase in hippocampal neurons.

[References]

References 1. Brand CS, et al. J Pharmacol Exp Ther. 2013 Nov;347(2):265-75. 2. Cheng Q, et al. Neuropharmacology. 2015 Aug;95:405-14. View Related Products by Target Adenylate Cyclase

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₉H₁₄N₄O₃

[ Molecular Weight ]:
346.346

Related Compounds

CB-25
CB 1640
CB 1743
CB-83
cb-2959
CB-002
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
tert-Butyl-DL-alanine
4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide
N-[3-(Aminooxy)propyl]-N-butyl-1-butanamine