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5-Methoxy-2-pyrrolidinone

Names

[ CAS No. ]:
38072-88-7

[ Name ]:
5-Methoxy-2-pyrrolidinone

[Synonym ]:
5-Methoxypyrrolidin-2-one
2-Pyrrolidinone, 5-methoxy-
Pterolactam
5-Methoxy-2-pyrrolidinone

Biological Activity

[Description]:

Pterolactam can be isolated from Chrysanthemum coronarium L. Pterolactam derivates serval analogues that Mannich bases of amide with antifungal activities and cytotoxicity[1][2].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Fungal

[References]

[1]. Song MC, et al. Heterocyclic compounds from Chrysanthemum coronarium L. and their inhibitory activity on hACAT-1, hACAT-2, and LDL-oxidation. Arch Pharm Res. 2008 May;31(5):573-8.  

[2]. Dascalu AE, et al. Design, synthesis and antifungal activity of pterolactam-inspired amide Mannich bases. Fitoterapia. 2020 Jun;143:104581.  

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
268.5±33.0 °C at 760 mmHg

[ Molecular Formula ]:
C5H9NO2

[ Molecular Weight ]:
115.13

[ Flash Point ]:
116.2±25.4 °C

[ Exact Mass ]:
115.063332

[ PSA ]:
38.33000

[ LogP ]:
-2.18

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.461

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds