Bacopaside II

Names

[ Name ]:
Bacopaside II

[Synonym ]:
BACOPASIDE II(SH)
Bacopaside II

Biological Activity

[Description]:

Bacopaside II, an extract from the medicinal herb Bacopa monnieri, blocks the Aquaporin-1 (AQP1) water channel and impairs migration of cells that express AQP1. Bacopaside II induces cell cycle arrest and apoptosis[1][2].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Cancer

[References]

[1]. Palethorpe HM, et al. The Aquaporin 1 Inhibitor Bacopaside II Reduces Endothelial Cell Migration and Tubulogenesis and Induces Apoptosis. Int J Mol Sci. 2018 Feb 26;19(3). pii: E653.

[2]. Smith E, et al. The Purified Extract from the Medicinal Plant Bacopa monnieri, Bacopaside II, Inhibits Growth of Colon Cancer Cells In Vitro by Inducing Cell Cycle Arrest and Apoptosis. Cells. 2018 Jul 21;7(7). pii: E81.

Chemical & Physical Properties

[ Density]:
1.43

[ Molecular Formula ]:
C₄₇H₇₆O₁₈

[ Molecular Weight ]:
929.09600

[ Exact Mass ]:
928.50300

[ PSA ]:
276.14000

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport