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Antitubercular agent-30

Names

[ CAS No. ]:
384857-54-9

[ Name ]:
Antitubercular agent-30

Biological Activity

[Description]:

Antitubercular agent-30 is an antibacterial agent against Mycobacterium tuberculosis (MIC=50 μg/mL). Antitubercular agent-30 has little cytotoxic effect on murine macrophage cells (LD85=~100 μg/mL)[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Bacterial

[In Vitro]

Antitubercular agent-30 (compound 16) (0.1-100 μg/mL; 18 h) 的浓度低于 10 μg/mL 时，对小鼠巨噬细胞无细胞毒作用[1]。

[References]

[1]. Silva Lourenço MC, et al. Synthesis and biological evaluation of N-(aryl)-2-thiophen-2-ylacetamides series as a new class of antitubercular agents. Bioorg Med Chem Lett. 2007 Dec 15;17(24):6895-8.  

Chemical & Physical Properties

[ Density]:
1.421±0.06 g/cm3(Predicted)

[ Boiling Point ]:
517.5±40.0 °C(Predicted)

[ Melting Point ]:
125-127 °C

[ Molecular Formula ]:
C12H10N2O3S

[ Molecular Weight ]:
262.28

[ Storage condition ]:
-20°C

Related Compounds