ue1654

Names

[ Name ]:
ue1654

Biological Activity

[Description]:

Gue1654 is a modulator of OXE-R. Gue1654 inhibits Gβγ but not Gα signaling triggered upon activation of Gα(i)-βγ by the chemoattractant receptor OXE-R. Gue1654 does not interfere nonspecifically with signaling directly at or downstream of Gβγ[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Blättermann S, et al. A biased ligand for OXE-R uncouples Gα and Gβγ signaling within a heterotrimer. Nat Chem Biol. 2012;8(7):631-638.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₁₇N₃OS₃

[ Molecular Weight ]:
447.59600

[ Exact Mass ]:
447.05300

[ PSA ]:
140.15000

[ LogP ]:
7.04800

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ RIDADR ]:
NONH for all modes of transport