DOPE
Names
[ CAS No. ]:
4004-05-1
[ Name ]:
DOPE
[Synonym ]:
DOPE
9-Octadecenoic acid, (1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester, (9Z,9'Z)-
Dioleoyl phosphoethanolamine
L-A-phosphatidylethanolamine dioleoyl
1,2-dioleoyl-sn-glycero-3-phosphatidylethanolamine
1,2-dioleoyl-sn-glycerol-3-phosphoethanolamine
3-SN-PHOSPHATIDYLETHANOLAMINE,1,2-DIDEOYL
MFCD00057986
1,2-di-O-oleoyl-sn-glycero-3-phosphatidylethanolamine
1,2-Dioleoyl-sn-glycero-3-phosphatidylethanolamine (DOPE)
2-Ammonioethyl (2R)-2,3-bis[(9Z)-9-octadecenoyloxy]propyl phosphate
1,2-dioleoyl-sn-glycero-3-phosphoethanoloamine
COATSOME ME-8181 (DOPE)
DIOLEOYL PHOSPHATIDYL ETHANOLAMINE
18:1 PE
Biological Activity
[Description]:
[Related Catalog]:
[Target]
IC50: helper lipid for liposome[1]
[In Vitro]
[References]
Chemical & Physical Properties
[ Density]:
1.008g/cm3
[ Boiling Point ]:
759.2±70.0 °C at 760 mmHg
[ Melting Point ]:
200 °C
[ Molecular Formula ]:
C41H78NO8P
[ Molecular Weight ]:
744.034
[ Flash Point ]:
413.0±35.7 °C
[ Exact Mass ]:
743.546509
[ PSA ]:
144.19000
[ LogP ]:
14.79
[ Vapour Pressure ]:
0.0±5.5 mmHg at 25°C
[ Index of Refraction ]:
1.484
MSDS
Safety Information
[ Symbol ]:
GHS06, GHS08
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H302-H315-H319-H331-H336-H351-H361d-H372
[ Precautionary Statements ]:
P261-P281-P305 + P351 + P338-P311
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
Xn: Harmful;
[ Risk Phrases ]:
R22;R38;R40;R48/20/22
[ Safety Phrases ]:
36/37
[ RIDADR ]:
UN 1888
[ Hazard Class ]:
6.1
[ HS Code ]:
2931900090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2931900090
[ Summary ]:
2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%
Articles
J. Virol. 89(10) , 5714-23, (2015)
Similar to other positive-strand RNA viruses, tombusviruses are replicated by the membrane-bound viral replicase complex (VRC). The VRC consists of the p92 virus-coded RNA-dependent RNA polymerase (Rd...
Insights from reconstitution reactions of COPII vesicle formation using pure components and low mechanical perturbation.Biol. Chem. 395(7-8) , 801-12, (2014)
As shape transformations of membranes are vital for intracellular trafficking, it is crucial to understand both the mechanics and the biochemistry of these processes. The interplay of these two factor...
Cell-penetrating antimicrobial peptides - prospectives for targeting intracellular infections.Pharm. Res. 32(5) , 1546-56, (2015)
To investigate the suitability of three antimicrobial peptides (AMPs) as cell-penetrating antimicrobial peptides.Cellular uptake of three AMPs (PK-12-KKP, SA-3 and TPk) and a cell-penetrating peptide ...