ONO-6126
Names
[ CAS No. ]:
401519-28-6
[ Name ]:
ONO-6126
[Synonym ]:
2-{4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-4-methyl-1-piperidinyl}-N-hydroxyacetamide
1-Piperidineacetamide, 4-[3-(cyclopentyloxy)-4-methoxyphenyl]-N-hydroxy-4-methyl-
Biological Activity
[Description]:
ONO-6126 is a potent and selective PDE4 inhibitor for the treatment of bronchial asthma and allergic conjunctivitis. COPD Phase 2 Discontinued
[References]
References 1. Giembycz MA. Br J Pharmacol. 2008 Oct;155(3):288-90. View Related Products by Target Phosphodiesterase (PDE) COPD
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Molecular Formula ]:
C20H27N3O4
[ Molecular Weight ]:
362.463
[ Exact Mass ]:
362.220551
[ LogP ]:
2.51
[ Index of Refraction ]:
1.550