BIO 8898
Names
[ CAS No. ]:
402564-79-8
[ Name ]:
BIO 8898
Biological Activity
[Description]:
BIO 8898 is a synthetic, CD40-CD154 co-stimulatory interaction inhibitor that inhibits the TNF family cytokine CD40L binding to CD40-Ig with a potency of IC50=25 uM; inhibits CD40L-dependent apoptosis in a cellular assay.
[References]
References 1. Silvian LF, et al. ACS Chem Biol. 2011 Jun 17;6(6):636-47. 2. Ganesan L, et al. Pharmazie. 2012 May;67(5):374-9. View Related Products by Target Other Targets
Chemical & Physical Properties
[ Molecular Formula ]:
C53H64N8O6
[ Molecular Weight ]:
909.145