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2-[bis(2-chloroethyl)aminomethyl]isoindole-1,3-dione

Names

[ CAS No. ]:
40478-25-9

[ Name ]:
2-[bis(2-chloroethyl)aminomethyl]isoindole-1,3-dione

[Synonym ]:
N-Bis-<2-chlor-ethyl>-aminomethyl-phthalimid

Chemical & Physical Properties

[ Density]:
1.37g/cm3

[ Boiling Point ]:
358.8ºC at 760 mmHg

[ Molecular Formula ]:
C13H14Cl2N2O2

[ Molecular Weight ]:
301.16800

[ Flash Point ]:
170.8ºC

[ Exact Mass ]:
300.04300

[ PSA ]:
40.62000

[ LogP ]:
1.95760

[ Index of Refraction ]:
1.591

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NR3397930
CHEMICAL NAME :
1H-Isoindole-1,3(2H)-dione, 2-((bis(2-chloroethyl)amino)methyl)-
CAS REGISTRY NUMBER :
40478-25-9
BEILSTEIN REFERENCE NO. :
1537968
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C13-H14-Cl2-N2-O2
MOLECULAR WEIGHT :
301.19

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intramuscular
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
40 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARPMAS Archiv der Pharmazie (Weinheim, Germany) (VCH Pub., Inc., 303 NW 12th Ave., Deerfield Beach, FL 33441) V.51-261, 1835-1923; V.305- 1972- Volume(issue)/page/year: 306,64,1973
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intramuscular
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
225 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARPMAS Archiv der Pharmazie (Weinheim, Germany) (VCH Pub., Inc., 303 NW 12th Ave., Deerfield Beach, FL 33441) V.51-261, 1835-1923; V.305- 1972- Volume(issue)/page/year: 306,64,1973

Related Compounds