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N-Desmethyl imatinib

Names

[ CAS No. ]:
404844-02-6

[ Name ]:
N-Desmethyl imatinib

[Synonym ]:
N-Desmethyl Gleevec
N-Desmethyl Imatinib
Norimatinib
Imatinib metabolite
N-{4-Methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl}-4-(piperazin-1-ylmethyl)benzamide
Imatinib Impurity 6(EP-C)
Imatinib metabolite N-Desmethyl Imatinib

Biological Activity

[Description]:

N-Desmethyl Imatinib is a metabolite of Imatinib, which is a multi-target inhibitor of v-Abl, c-Kit and PDGFR.

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Others

[Related Small Molecules]

Captisol | Cyclosporin A | H2DCFDA | 0MPTP hydrochloride | GW4869 | Etomoxir | TD139 | Mitoquinone mesylate | GSK2795039 | JC-1 | BAPTA-AM | AP 20187 | Setanaxib (GKT137831) | D-Luciferin | Crotaline

Chemical & Physical Properties

[ Density]:
1.269g/cm3

[ Melting Point ]:
99-101ºC

[ Molecular Formula ]:
C28H29N7O

[ Molecular Weight ]:
479.57600

[ Exact Mass ]:
479.24300

[ PSA ]:
95.07000

[ LogP ]:
4.66080

[ Index of Refraction ]:
1.676

[ Storage condition ]:
-20°C Freezer

Safety Information

[ Safety Phrases ]:
24/25

[ HS Code ]:
29339900

Related Compounds