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Pentitol,1,2:4,5-dianhydro-3-deoxy- (9CI)

Names

[ CAS No. ]:
4051-27-8

[ Name ]:
Pentitol,1,2:4,5-dianhydro-3-deoxy- (9CI)

[Synonym ]:
2,2'-Methylenebisoxirane
2-(oxiranylmethyl)-oxirane
1,4,5-Diepoxypentane
Oxirane,2'-methylenebis
1,2,4,5-Diepoxy-pentan
1,2,4,5-diepoxy-pentane
Pentane,1,2:4,5-diepoxy
1,4-pentadienediepoxide
1:4-Pentadiene dioxide
1,2:4,5-dianhydro-3-deoxypentitol

Chemical & Physical Properties

[ Density]:
1.218g/cm3

[ Boiling Point ]:
181ºC at 760mmHg

[ Molecular Formula ]:
C5H8O2

[ Molecular Weight ]:
100.11600

[ Flash Point ]:
60.9ºC

[ Exact Mass ]:
100.05200

[ PSA ]:
25.06000

[ LogP ]:
0.17410

[ Vapour Pressure ]:
1.18mmHg at 25°C

[ Index of Refraction ]:
1.504

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SA0370000
CAS REGISTRY NUMBER :
4051-27-8
LAST UPDATED :
199712
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C5-H8-O2
MOLECULAR WEIGHT :
100.13
WISWESSER LINE NOTATION :
T3OTJ B1- BT3OTJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
70 gm/kg/58W-I
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
76 gm/kg/63W-I
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application

MUTATION DATA

TEST SYSTEM :
Rodent - rat
DOSE/DURATION :
250 mg/kg
REFERENCE :
BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 6,235,1951

Synthetic Route

Precursor & DownStream


Related Compounds