5-Hydroxyplatyphyllone M

Names

[ Name ]:
5-Hydroxyplatyphyllone M

[Synonym ]:
3-Heptanone, 5-hydroxy-1,7-bis(4-hydroxyphenyl)-, (5S)-
hirsutanonol
5-Hydroxy-3-platyphyllone
7,7-diphenyl-4,5,6,6a-tetrahydro-1H,3H-pyrrolo<1,2-c>oxazol-2-one
(5S)-5-Hydroxy-1,7-bis(4-hydroxyphenyl)-3-heptanone

Biological Activity

[Description]:

Platyphyllonol (Platyphyllone) can be isolated from A. japonica. Platyphyllonol shows cytotoxic effects on MCF-7 cells with IC50 values of 46.9 μg/mL[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Ryu M, et al. Activation of JNK and p38 in MCF-7 Cells and the In Vitro Anticancer Activity of Alnus hirsuta Extract. Molecules. 2020 Feb 27;25(5):1073.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
575.2±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₉H₂₂O₄

[ Molecular Weight ]:
314.376

[ Flash Point ]:
315.7±26.6 °C

[ Exact Mass ]:
314.151794

[ PSA ]:
77.76000

[ LogP ]:
2.08

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.606

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2914501900

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2914501900

[ Summary ]:
2914501900 other ketone-phenols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%