Platinum,(1,2-ethanediamine-kN1,kN2)[propanedioato(2-)-kO1,kO3]-, (SP-4-2)-
Names
[ CAS No. ]:
41666-77-7
[ Name ]:
Platinum,(1,2-ethanediamine-kN1,kN2)[propanedioato(2-)-kO1,kO3]-, (SP-4-2)-
[Synonym ]:
1,3-Cyclopentadiene,1-ethyl-,zirconium complex
Chemical & Physical Properties
[ Boiling Point ]:
386.8ºC at 760 mmHg
[ Molecular Formula ]:
C5H8N2O4Pt
[ Molecular Weight ]:
355.20600
[ Flash Point ]:
201.9ºC
[ Exact Mass ]:
355.01300
[ PSA ]:
76.66000
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TP2505500
- CHEMICAL NAME :
- Platinum (II), (ethylenediammine)malonato-
- CAS REGISTRY NUMBER :
- 41666-77-7
- LAST UPDATED :
- 199509
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C5-H10-N2-O4-Pt
- MOLECULAR WEIGHT :
- 357.26
- WISWESSER LINE NOTATION :
- Z2Z &QV1VQ &-PT-
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 1080 ug/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - paresthesis Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other Enzymes
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 46,2148,1986
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 6 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- BICHBX Bioinorganic Chemistry. (New York, NY) V.1-9, 1971-78. Volume(issue)/page/year: 2,187,1973
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 107 mg/kg
- TOXIC EFFECTS :
- Gastrointestinal - other changes Kidney, Ureter, Bladder - other changes
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 46,2148,1986 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 120 mg/kg/5D-I
- TOXIC EFFECTS :
- Liver - other changes Blood - changes in bone marrow (not otherwise specified) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB80-217292