trans-3,5-Dimethoxy-4-hydroxy cinnamaldehyde

Names

[ Name ]:
trans-3,5-Dimethoxy-4-hydroxy cinnamaldehyde

[Synonym ]:
(2E)-3-(4-Hydroxy-3,5-dimethoxyphenyl)acrylaldehyde
(2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enal
2-Propenal, 3-(4-hydroxy-3,5-dimethoxyphenyl)-, (2E)-
2-Propenal, 3-(4-hydroxy-3,5-dimethoxyphenyl)-, (E)-
MFCD00075980
trans-3,5-Dimethoxy-4-hydroxycinnamaldehyde
sinapyl aldehyde
Trans-3,5-Dimethoxy-4-Hydroxy Cinnamaldehyde
Sinapinaldehyde

Biological Activity

[Description]:

Sinapaldehyde, isolated from the stems of Rhodamnia dumetorum, exhibits moderate antibacterial against Methicillin resistant S. aureus (MRSA) and E. coli with MIC values of 128 and 128 μg/mL[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Waranya Lakornwong, et al. A New Coruleoellagic Acid Derivative From Stems of Rhodamnia Dumetorum. Nat Prod Res. 2018 Jul;32(14):1653-1659.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
372.3±37.0 °C at 760 mmHg

[ Melting Point ]:
104-106ºC(lit.)

[ Molecular Formula ]:
C₁₁H₁₂O₄

[ Molecular Weight ]:
208.211

[ Flash Point ]:
146.3±20.0 °C

[ Exact Mass ]:
208.073563

[ PSA ]:
55.76000

[ LogP ]:
1.00

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.575

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2912499000

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2912499000

[ Summary ]:
2912499000. other aldehyde-ethers, aldehyde-phenols and aldehydes with other oxygen function. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

Articles

[Study on chemical constituents from ethyl acetate extract of Myricaria bracteata].

Zhongguo Zhong Yao Za Zhi 36(8) , 1019-23, (2011)

To study the chemical constituents from the ethyl acetate extract of Myricaria bracteata.The chemical constituents were isolated and purified by chromatographic techniques, and their structures were i...

A rapid sample screening method for authenticity control of whiskey using capillary electrophoresis with online preconcentration.

J. Agric. Food Chem. 59(13) , 6882-8, (2011)

The present study aimed to develop a methodology using capillary electrophoresis for the determination of sinapaldehyde, syringaldehyde, coniferaldehyde, and vanillin in whiskey samples. The main obje...

Influences of cinnamic aldehydes on H⁺ extrusion activity and ultrastructure of Candida.

J. Med. Microbiol. 62(Pt 2) , 232-40, (2013)

The antifungal effects of cinnamaldehyde, 4-hydroxy-3-methoxycinnamaldehyde (coniferyl aldehyde) and 3,5-dimethoxy-4-hydroxycinnamaldehyde (sinapaldehyde) were investigated against 65 strains of Candi...