N-Methyl-N-nitrosotoluene-4-sulfonamide-d3

Names

[ CAS No. ]:
42366-72-3

[ Name ]:
N-Methyl-N-nitrosotoluene-4-sulfonamide-d3

[Synonym ]:
4-methylcyclohexyl p-toluenesulfonate
p-Toluolsulfonsaeure-<nitroso-deuteromethylamid>
diazald-N-methyl-d3
MFCD00074893
4-Methyl-N-(H)methyl-N-nitrosobenzenesulfonamide
4-methylcyclohexyl 4-methylbenzenesulfonate
cyclohexanol,4-methyl-,4-methylbenzenesulfonate
Benzenesulfonic acid, 4-methyl-, 1-(methyl-d)-2-oxohydrazide

Biological Activity

[Description]:

N-Methyl-N-nitrosotoluene-4-sulfonamide-d3 is the deuterium labeled N-Methyl-N-nitrosotoluene-4-sulfonamide[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
320.5±35.0 °C at 760 mmHg

[ Melting Point ]:
60-63ºC

[ Molecular Formula ]:
C8H7D3N2O3S

[ Molecular Weight ]:
217.260

[ Flash Point ]:
147.6±25.9 °C

[ Exact Mass ]:
217.060043

[ PSA ]:
75.19000

[ LogP ]:
0.58

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.573

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H317-H319-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
20/21/22-43

[ Safety Phrases ]:
26-36

[ RIDADR ]:
UN3234 - UN3224 DOT class 4.1 (N-Methyl-N-nitroso-p-methylbenzenesulfonamide) Self-reactive solid type C, temperature controlled)

Related Compounds