[(2S,3R,4S)-1,3-dimethyl-2,4-diphenylpiperidin-4-yl] propanoate,hydrochloride
Names
[ CAS No. ]:
42473-48-3
[ Name ]:
[(2S,3R,4S)-1,3-dimethyl-2,4-diphenylpiperidin-4-yl] propanoate,hydrochloride
Chemical & Physical Properties
[ Molecular Formula ]:
C22H28ClNO2
[ Molecular Weight ]:
373.91600
[ Exact Mass ]:
373.18100
[ PSA ]:
29.54000
[ LogP ]:
5.28790
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TN6998780
- CHEMICAL NAME :
- Piperidin-4-axial-ol, 1,3-equatorial-dimethyl-2-equatorial,4-equatorial-dip henyl-, propionate (ester), hydrochloride
- CAS REGISTRY NUMBER :
- 42473-48-3
- LAST UPDATED :
- 198609
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C22-H27-N-O2.Cl-H
- MOLECULAR WEIGHT :
- 373.96
- WISWESSER LINE NOTATION :
- T6NTJ A1 BR& C1 DOV2 DR &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 150 mg/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex) Nutritional and Gross Metabolic - body temperature decrease
- REFERENCE :
- PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 15,20,1981