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H-Val-Pro-Leu-Ser-Leu-Tyr-Ser-Gly-OH trifluoroacetate salt

Names

[ CAS No. ]:
425632-67-3

[ Name ]:
H-Val-Pro-Leu-Ser-Leu-Tyr-Ser-Gly-OH trifluoroacetate salt

Biological Activity

[Description]:

VPLSLYSG is an octapeptide that can be degraded by matrix metalloproteinase-9 (MMP-9), MMP-1 and MMP-2. VPLSLYSG has potential applications in MMP substrates[1][2][3].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Metabolic Enzyme/Protease >> MMP

[References]

[1]. Suzuki H, et al. Accurate targeting of activated macrophages based on synergistic activation of functional molecules uptake by scavenger receptor and matrix metalloproteinase. ACS Chem Biol. 2008 Aug 15;3(8):471-9.  

[2]. Patterson J, et al. Enhanced proteolytic degradation of molecularly engineered PEG hydrogels in response to MMP-1 and MMP-2. Biomaterials. 2010 Oct;31(30):7836-45.  

[3]. Wieduwild R, et al. Assembling and decorating hyaluronan hydrogels with twin protein superglues to mimic cell-cell interactions. Biomaterials. 2018 Oct;180:253-264.  

Chemical & Physical Properties

[ Molecular Formula ]:
C39H62N8O12

[ Molecular Weight ]:
834.96

Related Compounds