Desomorphine

Controlled Substances

Psychoactive Drugs/Narcotic Drugs/Hypertoxic Chemicals/Non-Medical Use of Narcotic Drugs and Psychotropic Substances

Names

[ CAS No. ]:
427-00-9

[ Name ]:
Desomorphine

[Synonym ]:
Permonid
Morphinan-3-ol, 4,5-epoxy-17-methyl-, (5α)-
Dihydrodesoxymorphine-D
dihydro-6-deoxy-morphine
Dihydrodeoxymorphine
dihydro-deoxymorphine-D
(5a)-17-methyl-4,5-epoxymorphinan-3-ol
(5α)-17-Methyl-4,5-epoxymorphinan-3-ol
DEA No. 9055
Morphine,6-deoxy-7,8-dihydro
Desomorphine
krokodil
EINECS 207-045-7
4,5a-Epoxy-17-methylmorphinan-3-ol

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
426.1±45.0 °C at 760 mmHg

[ Melting Point ]:
189°

[ Molecular Formula ]:
C17H21NO2

[ Molecular Weight ]:
271.354

[ Flash Point ]:
211.5±28.7 °C

[ Exact Mass ]:
271.157227

[ PSA ]:
32.70000

[ LogP ]:
2.24

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.665

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QD1730000
CHEMICAL NAME :
Morphinan-3-ol, 4,5-alpha-epoxy-17-methyl-
CAS REGISTRY NUMBER :
427-00-9
LAST UPDATED :
199009
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C17-H21-N-O2
MOLECULAR WEIGHT :
271.39
WISWESSER LINE NOTATION :
T B6566 B6/CO 4ABBC R BX HO PN GHT&&TTJ JQ P1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
104 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - convulsions or effect on seizure threshold
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 55,257,1935
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
27 mg/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - local anesthetic Behavioral - altered sleep time (including change in righting reflex) Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 84,268,1964

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H302 + H332-H319

[ Precautionary Statements ]:
P210-P305 + P351 + P338

[ Hazard Codes ]:
F,Xn

[ Risk Phrases ]:
11-20/21/22-36

[ Safety Phrases ]:
16-36/37

[ RIDADR ]:
UN 1648 3 / PGII

Related Compounds