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1,1,2-trifluoroethane

Names

[ CAS No. ]:
430-66-0

[ Name ]:
1,1,2-trifluoroethane

[Synonym ]:
R 143
Ethane,1,1,2-trifluoro
1,2,2-trifluoroethane
CH2FCHF2
EINECS 207-066-1
MFCD00039280
1,1,2-trifluoro-ethane
FC 143

Chemical & Physical Properties

[ Density]:
1.073 g/cm3

[ Boiling Point ]:
5ºC

[ Melting Point ]:
-84ºC

[ Molecular Formula ]:
C2H3F3

[ Molecular Weight ]:
84.04040

[ Exact Mass ]:
84.01870

[ LogP ]:
1.22100

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KJ4110010
CHEMICAL NAME :
Ethane, 1,1,2-trifluoro-
CAS REGISTRY NUMBER :
430-66-0
BEILSTEIN REFERENCE NO. :
1731624
LAST UPDATED :
199710
DATA ITEMS CITED :
8
MOLECULAR FORMULA :
C2-H3-F3

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
25 gm/m3/6H
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - acute pulmonary edema Liver - other changes Kidney, Ureter, Bladder - other changes
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 8(10),21,1964
TYPE OF TEST :
LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
25 gm/m3/4H
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - acute pulmonary edema Liver - other changes Kidney, Ureter, Bladder - other changes
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 8(10),21,1964 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
50 mg/m3/4H/17W-I
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - acute pulmonary edema Liver - changes in liver weight Kidney, Ureter, Bladder - other changes
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 8(10),21,1964
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
50 mg/m3/4H/17W-I
TOXIC EFFECTS :
Behavioral - alteration of classical conditioning Lungs, Thorax, or Respiration - acute pulmonary edema Blood - changes in spleen
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 8(10),21,1964
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
50 mg/m3/4H/17W-I
TOXIC EFFECTS :
Vascular - BP lowering not characterized in autonomic section Liver - changes in liver weight Endocrine - changes in thyroid weight
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 8(10),21,1964
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
50 mg/m3/4H/17W-I
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - acute pulmonary edema Liver - other changes Kidney, Ureter, Bladder - other changes
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 8(10),21,1964

Safety Information

[ Hazard Codes ]:
F: Flammable;

[ Risk Phrases ]:
R11

[ Safety Phrases ]:
16-33

[ RIDADR ]:
UN 3161

[ Hazard Class ]:
2.1

[ HS Code ]:
2903399090

Precursor & DownStream

Customs

[ HS Code ]: 2903399090

[ Summary ]:
2903399090. brominated,fluorinated or iodinated derivatives of acyclic hydrocarbons. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%


Related Compounds