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(Deamino-Cys1,Val4,D-Arg8)-Vasopressin

Names

[ CAS No. ]:
43157-23-9

[ Name ]:
(Deamino-Cys1,Val4,D-Arg8)-Vasopressin

[Synonym ]:
Val4-dDAVP
[deamino-Cys1,Val4,D-Arg8]-vasopressin
DVDAVP
3-MERCAPTOPROPIONYL-TYR-PHE-VAL-ASN-CYS-PRO-D-ARG-GLY-NH2
[MPR1,VAL4,DARG8] VASOPRESSIN
1-Deamino-4-L-valine-8D-arginine vasopressin
dVDAVP,(Val4)-DesMopressin
2-Deamino-L-Cys(1)-L-Tyr-L-Phe-L-Val-L-Asn-L-Cys(1)-L-Pro-D-Arg-Gly-NH2
3-MERCAPTOPROPIONYL-TYR-PHE-VAL-ASN-CYS-PRO-ARG-GLY-NH2
1-deamino-4-valine-8-D-arginine-vasopressin
MPR-TYR-PHE-VAL-ASN-CYS-PRO-DARG-GLY-NH2

Biological Activity

[Description]:

[Deamino-4-valine, 8-D-arginine]-Vasopressin (dVDAVP) is a highly potent and specific antidiuretic agent possessing protracted effects[1][2].

[Related Catalog]:

Research Areas >> Endocrinology
Signaling Pathways >> Others >> Others

[References]

[1]. M Manning, et al. [1-deaminopenicillamine,4-valine]-8-D-arginine-vasopressin, a highly potent inhibitor of the vasopressor response to arginine-vasopressin. J Med Chem. 1977 Sep;20(9):1228-30.  

[2]. M Manning, et al. Solid phase synthesis of (1-deamino,4-valine)-8-D-arginine-vasopressin (DVDAVP), a highly potent and specific antidiuretic agent possessing protracted effects. J Med Chem. 1973 Sep;16(9):975-8.  

Chemical & Physical Properties

[ Molecular Formula ]:
C46H65N13O11S2

[ Molecular Weight ]:
1040.22000

[ Exact Mass ]:
1039.44000

[ PSA ]:
442.92000

[ LogP ]:
2.21370

Synthetic Route

Click to get detail synthetic route

Related Compounds