SSAA09E1

Names

[ Name ]:
SSAA09E1

[Synonym ]:
Hydrazinecarbothioamide, 2-[1-(2-thienyl)ethylidene]-, (2Z)-
(2Z)-2-[1-(2-Thienyl)ethylidene]hydrazinecarbothioamide
(2Z)-2-[1-(thiophen-2-yl)ethylidene]hydrazinecarbothioamide
SSAA09E1
2-[1-(2-thienyl)ethylidene]hydrazine-1-carbothioamide

Biological Activity

[Description]:

SSAA09E1 is a cathepsin L blocker (IC50: 5.33 μM).SSAA09E1 inhibits stages of viral entry. SSAA09E1 can be used for SARS-CoV infection research[1]

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> SARS-CoV

Signaling Pathways >> Metabolic Enzyme/Protease >> Cathepsin

[Target]

5.33 μM (cathepsin L)[1]

[References]

[1]. Adedeji AO, et al. Novel inhibitors of severe acute respiratory syndrome coronavirus entry that act by three distinct mechanisms. J Virol. 2013 Jul;87(14):8017-28.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
333.0±34.0 °C at 760 mmHg

[ Molecular Formula ]:
C₇H₉N₃S₂

[ Molecular Weight ]:
199.296

[ Flash Point ]:
155.2±25.7 °C

[ Exact Mass ]:
199.023788

[ LogP ]:
0.92

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.686