H-DL-Leu-Gly-Gly-OH

Names

[ CAS No. ]:
4337-37-5

[ Name ]:
H-DL-Leu-Gly-Gly-OH

[Synonym ]:
EINECS 224-384-6
MFCD00064990
DL-Leucylglycylglycine
H-DL-Leu-Gly-Gly-OH
DL-Leu-Gly-Gly

Biological Activity

[Description]:

2-(2-(2-Amino-4-methylpentanamido)acetamido)acetic acid is a Glycine (HY-Y0966) derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Density]:
1.199g/cm3

[ Boiling Point ]:
573.7ºC at 760mmHg

[ Melting Point ]:
>240℃ (water ethanol )

[ Molecular Formula ]:
C₁₀H₁₉N₃O₄

[ Molecular Weight ]:
245.27600

[ Flash Point ]:
300.8ºC

[ Exact Mass ]:
245.13800

[ PSA ]:
121.52000

[ LogP ]:
0.15890

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Precursor & DownStream

Precursor

DownStream

Articles

Separation of N-derivatized di- and tri-peptide stereoisomers by micro-liquid chromatography using a quinidine-based monolithic column - Analysis of l-carnosine in dietary supplements.

J. Chromatogr. A. 1428 , 176-84, (2016)

In the present study, a new analytical methodology was developed enabling the enantiomeric determination of N-derivatized di- and tri-peptides in dietary supplements using chiral micro-LC on a monolit...

Characterization of the pattern of alphas1- and beta-casein breakdown and release of a bioactive peptide by a cell envelope proteinase from Lactobacillus delbrueckii subsp. lactis CRL 581.

Appl. Environ. Microbiol. 74 , 3682-3689, (2008)

The cell envelope-associated proteinases (CEPs) of the lactobacilli have key roles in bacterial nutrition and contribute to the development of the organoleptic properties of fermented milk products as...

Release of the cell-envelope-associated proteinase of Lactobacillus delbrueckii subspecies lactis CRL 581 is dependent upon pH and temperature.

J. Agric. Food Chem. 57 , 8607-8611, (2009)

The cell-envelope-associated proteinase of Lactobacillus delbrueckii subsp. lactis CRL 581 (PrtL) has an essential role in bacterial growth and contributes to the development of the organoleptic prope...