(Des-Bromo)-Neuropeptide B (1-23) (human) trifluoroacetate salt

Names

[ Name ]:
(Des-Bromo)-Neuropeptide B (1-23) (human) trifluoroacetate salt

[Synonym ]:
H-TRP-TYR-LYS-PRO-ALA-ALA-GLY-HIS-SER-SER-TYR-SER-VAL-GLY-ARG-ALA-ALA-GLY-LEU-LEU-SER-GLY-LEU-OH
DESBR-NPB-23 (HUMAN)
(Des-BroMo)-Neuropeptide B (1-23) (huMan) DesBr-NPB-23 (huMan)

Biological Activity

[Description]:

(Des-Bromo)-Neuropeptide B (1-23) (human) is an orphan G-protein coupled receptor agonist with Kis of 1.2 nM and 341 nM for GPR7 (NPBW1) and GPR8 (NPBW2), respectively[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Neurological Disease

[Target]

Ki: 1.2 nM (GPR7), 341 nM (GPR8)[1]

[References]

[1]. Kanesaka M, et al. Development of a potent and selective GPR7 (NPBW1) agonist: a systematic structure-activity study of neuropeptide B. J Pept Sci. 2007 Jun;13(6):379-85.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₀₇H₁₆₂N₃₀O₃₀

[ Molecular Weight ]:
2348.61

[ Exact Mass ]:
2347.21000

[ PSA ]:
948.50000

[ LogP ]:
0.65580