8-azidoadenosine

Names

[ Name ]:
8-azidoadenosine

[Synonym ]:
8-azidoadenosine

Biological Activity

[Description]:

8-Azidoadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.

Chemical & Physical Properties

[ Melting Point ]:
>200ºC (dec.)

[ Molecular Formula ]:
C₁₀H₁₂N₈O₄

[ Molecular Weight ]:
308.25

[ Exact Mass ]:
308.09800

[ PSA ]:
189.29000

[ Storage condition ]:
Amber Vial, Refrigerator, Under Inert Atmosphere

8-azidoadenosine

Names

Biological Activity

Chemical & Physical Properties

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds