9-α-FLUORO-17-α-METHYL-17-HYDROXY-4-ANDROSTENE-3,11-DIONE
Names
[ CAS No. ]:
465-69-0
[ Name ]:
9-α-FLUORO-17-α-METHYL-17-HYDROXY-4-ANDROSTENE-3,11-DIONE
[Synonym ]:
Androst-4-ene-3,11-dione,9-fluoro-17beta-hydroxy-17-methyl
9-Fluoro-17-methyl-11-oxotestosterone
androst-4-ene-3,11-dione,9-fluoro-17|A-hydroxy-17-methyl
9alpha-Fluoro-17alpha-methyl-17-hydroxy-4-androstene-3,11-dione
Testosterone,9-fluoro-17-methyl-11-oxo
Chemical & Physical Properties
[ Density]:
1.21g/cm3
[ Boiling Point ]:
466.1ºC at 760 mmHg
[ Molecular Formula ]:
C20H27FO3
[ Molecular Weight ]:
334.42500
[ Flash Point ]:
235.7ºC
[ Exact Mass ]:
334.19400
[ PSA ]:
54.37000
[ LogP ]:
3.54040
[ Vapour Pressure ]:
1.2E-10mmHg at 25°C
[ Index of Refraction ]:
1.554
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- BV8151500
- CHEMICAL NAME :
- Androst-4-ene-3,11-dione, 9-fluoro-17-beta-hydroxy-17-methyl-
- CAS REGISTRY NUMBER :
- 465-69-0
- BEILSTEIN REFERENCE NO. :
- 3163272
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C20-H27-F-O3
- MOLECULAR WEIGHT :
- 334.47
- WISWESSER LINE NOTATION :
- L E5 B666 CV OV MUTJ A1 BF E1 FQ F1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 800 mg/kg
- SEX/DURATION :
- female 3-10 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Fertility - abortion
- REFERENCE :
- JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960- Volume(issue)/page/year: 39,319,1974
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 500 mg/kg
- SEX/DURATION :
- female 3-7 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth)
- REFERENCE :
- JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960- Volume(issue)/page/year: 39,319,1974
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 12 mg/kg
- SEX/DURATION :
- female 3 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - uterus, cervix, vagina
- REFERENCE :
- JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960- Volume(issue)/page/year: 39,319,1974