2’-Deoxy-2’-iodouridine; 2’-Iodo-2’-deoxyuridine

Names

[ CAS No. ]:
4753-03-1

[ Name ]:
2’-Deoxy-2’-iodouridine; 2’-Iodo-2’-deoxyuridine

[Synonym ]:
Uridine,2'-deoxy-2'-iodo
2'-deoxy-2'-iodouridine
Uridine,2'-deoxy-2'-iodo-(7CI,8CI,9CI)
2'-Iodo-2'-deoxyuridine

Biological Activity

[Description]:

2’-Deoxy-2’-iodouridine; 2’-Iodo-2’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Molecular Formula ]:
C9H11IN2O5

[ Molecular Weight ]:
354.10

[ Exact Mass ]:
353.97100

[ PSA ]:
104.81000

Related Compounds