5'-Deoxyadenosine

Names

[ Name ]:
5'-Deoxyadenosine

[Synonym ]:
5AD
CH33ADO
(2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-methyloxolane-3,4-diol
CH3Ado
5'-Deoxyadenosine
5-DEOXYADENOSINE

Biological Activity

[Description]:

5'-Deoxyadenosine is an oxidized nucleoside found in the urine of normal subjects.

[Related Catalog]:

Natural Products >> Others

Research Areas >> Others

[Target]

Human Endogenous Metabolite

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.93g/cm3

[ Boiling Point ]:
595ºC at 760 mmHg

[ Melting Point ]:
210-212 °C

[ Molecular Formula ]:
C₁₀H₁₃N₅O₃

[ Molecular Weight ]:
251.24200

[ Flash Point ]:
313.6ºC

[ Exact Mass ]:
251.10200

[ PSA ]:
119.31000

[ Index of Refraction ]:
1.867

[ Storage condition ]:
2-8°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AU7358650

CHEMICAL NAME :: Adenosine, 5'-deoxy-

CAS REGISTRY NUMBER :: 4754-39-6

BEILSTEIN REFERENCE NO. :: 0091536

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C10-H13-N5-O3

MOLECULAR WEIGHT :: 251.28

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation test systems - not otherwise specified

TEST SYSTEM :: Rodent - mouse Leukocyte

DOSE/DURATION :: 278 umol/L

REFERENCE :: CCCCAK Collection of Czechoslovak Chemical Communications. (Academic Press Inc. Ltd., 24-28 Oval Rd., London NW1 7DX, UK) V.1- 1929- Volume(issue)/page/year: 49,2551,1984

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
AU7358650

Synthetic Route

Click to get detail synthetic route

Articles

Characterization of RimO, a new member of the methylthiotransferase subclass of the radical SAM superfamily.

Biochemistry 48(42) , 10162-74, (2009)

RimO, encoded by the yliG gene in Escherichia coli, has been recently identified in vivo as the enzyme responsible for the attachment of a methylthio group on the beta-carbon of Asp88 of the small rib...

The ONIOM Method and Its Applications.

Chem. Rev. 115 , 5678-796, (2015)

Radical triplets and suicide inhibition in reactions of 4-thia-D- and 4-thia-L-lysine with lysine 5,6-aminomutase.

Biochemistry 48(34) , 8151-60, (2009)

Lysine 5,6-aminomutase (5,6-LAM) catalyzes the interconversions of D- or L-lysine and the corresponding enantiomers of 2,5-diaminohexanoate, as well as the interconversion of L-beta-lysine and l-3,5-d...