(-)-Isocorypalmine

Names

[ CAS No. ]:
483-34-1

[ Name ]:
(-)-Isocorypalmine

[Synonym ]:
(13aS)-3,9,10-Trimethoxy-5,8,13,13a-tetrahydro-6H-isoquinolino[3,2-a]isoquinolin-2-ol
(-)-Isocorypalmine
(S)-3,9,10-Trimethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[3,2-a]isoquinolin-2-ol
6H-Dibenzo[a,g]quinolizin-2-ol, 5,8,13,13a-tetrahydro-3,9,10-trimethoxy-, (13aS)-

Biological Activity

[Description]:

(-)-Isocorypalmine, an alkaloid isolated from Corydalis chaerophylla, possesses antifungal activity[1].

[Related Catalog]:

Research Areas >> Infection

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Sangita Sahni, et al. Inhibitory Effect of Two Alkaloids, (–)-Corydalmine and (–)-Isocorypalmine Isolated from Corydalis chaerophylla on Several Phytopathogenic Fungi Sangita Sahni. Mycobiology. 2018 Jun.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
501.2±50.0 °C at 760 mmHg

[ Melting Point ]:
240-241℃

[ Molecular Formula ]:
C₂₀H₂₃NO₄

[ Molecular Weight ]:
341.401

[ Flash Point ]:
256.9±30.1 °C

[ Exact Mass ]:
341.162720

[ PSA ]:
51.16000

[ LogP ]:
2.93

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.640

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NQ7685000

CHEMICAL NAME :: Isocorypalmine, (-)-

CAS REGISTRY NUMBER :: 483-34-1

LAST UPDATED :: 199709

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C20-H23-N-O4

MOLECULAR WEIGHT :: 341.44

WISWESSER LINE NOTATION :: T D6 B666 KN&TT&J GO1 HO1 PO1 QQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 133 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FEPRA7 Federation Proceedings, Federation of American Societies for Experimental Biology. (Bethesda, MD) V.1-46, 1942-87. Volume(issue)/page/year: 5,163,1946

Safety Information

[ HS Code ]:
2933990090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%