NMDA receptor potentiator-1

Names

[ CAS No. ]:
486427-18-3

[ Name ]:
NMDA receptor potentiator-1

Biological Activity

[Description]:

NMDA receptor potentiator-1 (Compound 1368) is a subunit selective NMDA receptor potentiator with IC50s of 4 μM and 5 μM against NR2C and NR2D expression, respectively[1].

[Related Catalog]:

Signaling Pathways >> Neuronal Signaling >> iGluR
Research Areas >> Neurological Disease
Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR

[Target]

NR2C:4 μM (IC50)

NR2D:5 μM (IC50)


[References]

[1]. Stephen F. Traynelis, et al. Subunit selective NMDA receptor potentiators for the treatment of neurological conditions. Patent US8822462.

Chemical & Physical Properties

[ Molecular Formula ]:
C26H26ClNO5

[ Molecular Weight ]:
467.94

Related Compounds