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Butin

Names

[ CAS No. ]:
492-14-8

[ Name ]:
Butin

[Synonym ]:
5-Deoxyeriodictyol
(-)-butin
(2S)-2-(3,4-Dihydroxyphenyl)-7-hydroxy-2,3-dihydro-4H-chromen-4-one
4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-, (2S)-
4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-, (S)-
7,3',4'-Trihydroxyflavanone
(2S)-2-(3,4-dihydroxyphenyl)-7-hydroxy-2,3-dihydrochromen-4-one
Butin
3',4',7-Trihydroxyflavanone

Biological Activity

[Description]:

(-)-Butin is the S enantiomer of Butin. Butin is a major biologically active flavonoid isolated from the heartwood of Dalbergia odorifera, with strong antioxidant, antiplatelet and anti-inflammatory activities[1][2].

[Related Catalog]:

Signaling Pathways >> Others >> Others

[References]

[1]. Duan J, et al. Protective effect of butin against ischemia/reperfusion-induced myocardial injury in diabetic mice: involvement of the AMPK/GSK-3β/Nrf2 signaling pathway. Sci Rep. 2017 Jan 27;7:41491.

[2]. Li P, et al. Butin Attenuates Brain Edema in a Rat Model of Intracerebral Hemorrhage by Anti Inflammatory Pathway. Transl Neurosci. 2018 May 8;9:7-12.

Chemical & Physical Properties

[ Density]:
1.485

[ Boiling Point ]:
582.4±50.0 °C at 760 mmHg

[ Melting Point ]:
224-226ºC

[ Molecular Formula ]:
C15H12O5

[ Molecular Weight ]:
272.253

[ Flash Point ]:
226.7±23.6 °C

[ Exact Mass ]:
272.068481

[ PSA ]:
86.99000

[ LogP ]:
2.16

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.693

Safety Information

[ Hazard Codes ]:
Xi


Related Compounds