Statine

Names

[ Name ]:
Statine

[Synonym ]:
h-sta-oh
statin
MFCD00037277

Biological Activity

[Description]:

Statine is an unusual amino acid that occurs twice in the sequence of pepstatin, a protease inhibitor that is active against pepsin and other acid proteases.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Endocrinology

[In Vitro]

Statine is an unusual amino acid that occurs twice in the sequence of pepstatin, a protease inhibitor that is active against pepsin and other acid proteases. Statine is also an analog of the previously proposed transition state for catalysis by pepsin and other acid proteases[1].

[References]

[1]. Marciniszyn J Jr, et al. Mode of inhibition of acid proteases by pepstatin. J Biol Chem. 1976 Nov 25;251(22):7088-94.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.112 g/cm3

[ Boiling Point ]:
355.1ºC at 760 mmHg

[ Melting Point ]:
209ºC

[ Molecular Formula ]:
C₈H₁₇NO₃

[ Molecular Weight ]:
175.22500

[ Flash Point ]:
168.5ºC

[ Exact Mass ]:
175.12100

[ PSA ]:
83.55000

[ LogP ]:
0.89570

[ Index of Refraction ]:
1.49

Safety Information

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-36

[ HS Code ]:
2922509090

Customs

[ HS Code ]: 2922509090

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%