Pomalidomide-7-NH2
Names
[ CAS No. ]:
497146-96-0
[ Name ]:
Pomalidomide-7-NH2
Biological Activity
[Description]:
Pomalidomide-7-NH2 is the Pomalidomide-based cereblon ligand used in the recruitment of CRBN protein. Pomalidomide-7-NH2 can be connected to the ligand for protein by a linker to form PROTACs[1].
[Related Catalog]:
[Target]
Cereblon
[In Vitro]
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C13H12N4O4
[ Molecular Weight ]:
288.26
[ Storage condition ]:
2-8°C