Ethyl nipecotate
Names
[ CAS No. ]:
5006-62-2
[ Name ]:
Ethyl nipecotate
[Synonym ]:
3-Piperidinecarboxylic acid, ethyl ester, (±)-
Ethyl nipecotate
Ethyl 3-piperidinecarboxylate
Nipecotinic acid ethyl ester
ethyl piperidine-3-carboxylate
Ethylpiperidin-3-carboxylat
3-Piperidinecarboxylic acid ethyl ester
EINECS 225-681-3
3-Piperidinecarboxylic acid, ethyl ester
MFCD00005991
Ethylpiperidine-3-carboxylate
nipecotic acid ethyl ester
(±)-ETHYL NIPECOTATE
Chemical & Physical Properties
[ Density]:
1.0±0.1 g/cm3
[ Boiling Point ]:
238.6±0.0 °C at 760 mmHg
[ Molecular Formula ]:
C8H15NO2
[ Molecular Weight ]:
157.210
[ Flash Point ]:
90.6±0.0 °C
[ Exact Mass ]:
157.110275
[ PSA ]:
38.33000
[ LogP ]:
0.96
[ Vapour Pressure ]:
0.0±0.4 mmHg at 25°C
[ Index of Refraction ]:
1.449
[ Water Solubility ]:
miscible
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xi,C
[ Risk Phrases ]:
R34
[ Safety Phrases ]:
S26-S36/37/39-S45
[ WGK Germany ]:
3
[ HS Code ]:
2933399090
Customs
[ HS Code ]: 2933399090
[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
Chirality 7 , 90, (1995)
The stereoisomers of alpha,alpha'-bis[3-(N,N-diethylcarbamoyl)-piperidino]-p-xylene (1) were synthesized. Rac ethyl nipecotate was resolved by diastereomeric (-)-D- and (+)-L-tartrate salt formation. ...
THIP analgesia: cross tolerance with morphine.Life Sci. 32(19) , 2265-72, (1983)
THIP (4,5,6,7-tetrahydroisoxazolo (5,4-c) pyridone-3-ol), a direct acting GABA receptor agonist, has been shown to have antinociceptive properties. To determine whether tolerance develops to the analg...
(R)-nipecotic acid ethyl ester: a direct-acting cholinergic agonist that displays greater efficacy at M2 than at M1 muscarinic receptors.J. Pharmacol. Exp. Ther. 242(1) , 173-8, (1987)
Previous reports have suggested that the ethyl ester of (R)-nipecotic acid ethyl ester [(R)-NAEE] displays cholinomimetic properties in vivo. The present study was undertaken to characterize more full...